My work is in the education/publicity line, so I often have to tell the audience what they are supposed to be doing (as if it works). For about a million times I've tried telling my bosses that talking down and preaching doesn't cut it, especially w.r.t. health issues which already are very dry.
Take a look at "Syphillis Girl", a spoof of "Promiscuous Girl" by Nelly Furtado. That's the way to get our message across!
The actual video here:
Here's another good spoof ad. There's just something hilarious about preppy British people trying to do street talk.